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@0xMuluh 0xMuluh commented Dec 8, 2025

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Comment on lines +20 to +21
#' By default \code{scater::calculateMDS} keeps only the \code{ntop = 500}
#' most variable features. When rarefaction is enabled (\code{niter > 0}) the
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does the R code throw a warning of this if it does not use all features? (if data has more than 500)

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As we have mia::getMDS and mia::addMDS, we could set the default to no filtering. At least, I have not heard that variance filtering is commonly used in MDS in microbiome context (or then authors of papers have not explicitly stated that)

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