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AF3 runtime higher than reported for pool of proteins with 5000 tokens

questionFurther information is requestedFurther information is requested

Status: Open.

#609 In google-deepmind/alphafold3;

· karchern opened on Jan 30, 2026

inconsistent dev-requirements.txt when pyproject.toml ? xprof==2.21.3

setupProblem with installation or setting things upProblem with installation or setting things up

Status: Open.

#593 In google-deepmind/alphafold3;

· truatpasteurdotfr opened on Jan 12, 2026

OOM issues with 4608 and 5120 buckets

questionFurther information is requestedFurther information is requested

Status: Open.

#576 In google-deepmind/alphafold3;

· gdlampe opened on Dec 19, 2025

AF3 cannot predict correct ligand isomer even using userCDD

questionFurther information is requestedFurther information is requested

Status: Open.

#527 In google-deepmind/alphafold3;

· antonielgomes opened on Sep 26, 2025

Unified memory for extra large systems - rematerialization problems

questionFurther information is requestedFurther information is requested

Status: Open.

#432 In google-deepmind/alphafold3;

· GorgetteGorg opened on May 28, 2025

new release tag request

enhancementNew feature or requestNew feature or request

Status: Open.

#395 In google-deepmind/alphafold3;

· sky1ove opened on Apr 26, 2025

5746 tokens job: RESOURCE_EXHAUSTED (H100 80G, despite unified memory, jax flag and increase bucket size)

questionFurther information is requestedFurther information is requested

Status: Open.

#341 In google-deepmind/alphafold3;

· GitCeliniHub opened on Mar 9, 2025

Adding Docker image to container registry

enhancementNew feature or requestNew feature or request

Status: Open.

#322 In google-deepmind/alphafold3;

· VRehnberg opened on Feb 24, 2025

RuntimeWarning: overflow encountered in reduce

questionFurther information is requestedFurther information is requested

Status: Open.

#236 In google-deepmind/alphafold3;

· wtni-gidle opened on Dec 26, 2024

Bond order information missing in output cif files.

enhancementNew feature or requestNew feature or request

questionFurther information is requestedFurther information is requested

Status: Open.

#189 In google-deepmind/alphafold3;

· alchemistcai opened on Dec 7, 2024

AF3 unable to predict covalent bonds between DNA and protein

enhancementNew feature or requestNew feature or request

Status: Open.

#152 In google-deepmind/alphafold3;

· alchemistcai opened on Dec 1, 2024

First issue! Just want to say thank you!

good first issueGood for newcomersGood for newcomers

Status: Open.

#1 In google-deepmind/alphafold3;

· WillHua127 opened on Nov 11, 2024