In speaking with @robwormald the Angular folks are forced to swap between rxjs and rxjs-es during their build to enable proper tree-shaking. This is probably less than ideal. If all of the es6 files were under the same directories as .mjs files, then it would be as easy as configuring the bundler to look at that file extension to use ES6 modules.
This would mean that the rxjs-es build would likely not have a use anymore.
cc/ @IgorMinar @jeffbcross @bradlygreen