diff --git a/pep_sphinx_extensions/pep_processor/transforms/pep_headers.py b/pep_sphinx_extensions/pep_processor/transforms/pep_headers.py
index 57997c6b019..125966e10e0 100644
--- a/pep_sphinx_extensions/pep_processor/transforms/pep_headers.py
+++ b/pep_sphinx_extensions/pep_processor/transforms/pep_headers.py
@@ -131,6 +131,8 @@ def apply(self) -> None:
                 new_body = []
                 for pep_str in re.split(r",?\s+", body.astext()):
                     target = self.document.settings.pep_url.format(int(pep_str))
+                    if self.document.settings.builder == "dirhtml":
+                        target = f"../{target}"
                     new_body += [nodes.reference("", pep_str, refuri=target), nodes.Text(", ")]
                 para[:] = new_body[:-1]  # drop trailing space
             elif name == "topic":