diff --git a/CHANGELOG.md b/CHANGELOG.md
index b6fc20705b8..55e880c1802 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -2,6 +2,10 @@
 
 ## Perf
 
+### 2025-11-17
+
+- Configure BlobDB cache for account bytecodes [#5366](https://github.com/lambdaclass/ethrex/pull/5366)
+
 ### 2025-11-13
 
 - Use specialized DUP implementation [#5324](https://github.com/lambdaclass/ethrex/pull/5324)
diff --git a/crates/storage/store_db/rocksdb.rs b/crates/storage/store_db/rocksdb.rs
index 4792bd446fd..07a8a6a2807 100644
--- a/crates/storage/store_db/rocksdb.rs
+++ b/crates/storage/store_db/rocksdb.rs
@@ -312,6 +312,9 @@ impl Store {
                     cf_opts.set_min_blob_size(32);
                     cf_opts.set_blob_compression_type(rocksdb::DBCompressionType::Lz4);
 
+                    let blob_cache = rocksdb::Cache::new_lru_cache(128 * 1024 * 1024); // 128MB
+                    cf_opts.set_blob_cache(&blob_cache);
+
                     let mut block_opts = BlockBasedOptions::default();
                     block_opts.set_block_size(32 * 1024); // 32KB
                     cf_opts.set_block_based_table_factory(&block_opts);