diff --git a/CHANGELOG.md b/CHANGELOG.md
index 6e7269387f8..0fb72557f80 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -2,6 +2,9 @@
 
 ## Perf
 
+### 2025-11-10
+- Disable RocksDB compression [#5223](https://github.com/lambdaclass/ethrex/pull/5223)
+
 ### 2025-11-07
 - Reuse stack pool in LEVM [#5179](https://github.com/lambdaclass/ethrex/pull/5179)
 
diff --git a/Cargo.lock b/Cargo.lock
index 9812ca093ff..aad79076d67 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -5704,8 +5704,6 @@ dependencies = [
  "cc",
  "libc",
  "libz-sys",
- "lz4-sys",
- "zstd-sys",
 ]
 
 [[package]]
@@ -5934,16 +5932,6 @@ version = "0.1.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "112b39cec0b298b6c1999fee3e31427f74f676e4cb9879ed1a121b43661a4154"
 
-[[package]]
-name = "lz4-sys"
-version = "1.11.1+lz4-1.10.0"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "6bd8c0d6c6ed0cd30b3652886bb8711dc4bb01d637a68105a3d5158039b418e6"
-dependencies = [
- "cc",
- "libc",
-]
-
 [[package]]
 name = "malachite"
 version = "0.4.22"
diff --git a/Cargo.toml b/Cargo.toml
index 7fba81ef907..2a250fa1caa 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -119,7 +119,7 @@ uuid = { version = "1.18.1", features = ["v4"] }
 tower-http = { version = "0.6.2", features = ["cors"] }
 indexmap = { version = "2.11.4" }
 
-rocksdb = "0.24.0"
+rocksdb = { version="0.24.0", default-features = false, features = ["bindgen-runtime"] }
 
 [patch.crates-io]
 secp256k1 = { git = "https://github.com/sp1-patches/rust-secp256k1", tag = "patch-0.30.0-sp1-5.0.0" }
diff --git a/crates/storage/store_db/rocksdb.rs b/crates/storage/store_db/rocksdb.rs
index a49bf7c270e..a7a23c047ef 100644
--- a/crates/storage/store_db/rocksdb.rs
+++ b/crates/storage/store_db/rocksdb.rs
@@ -180,6 +180,8 @@ impl Store {
         db_options.set_enable_write_thread_adaptive_yield(true);
         db_options.set_compaction_readahead_size(4 * 1024 * 1024); // 4MB
         db_options.set_advise_random_on_open(false);
+        db_options.set_compression_type(rocksdb::DBCompressionType::None);
+        db_options.set_bottommost_compression_type(rocksdb::DBCompressionType::None);
 
         // db_options.enable_statistics();
         // db_options.set_stats_dump_period_sec(600);
@@ -239,10 +241,10 @@ impl Store {
             cf_opts.set_level_zero_file_num_compaction_trigger(4);
             cf_opts.set_level_zero_slowdown_writes_trigger(20);
             cf_opts.set_level_zero_stop_writes_trigger(36);
+            cf_opts.set_compression_type(rocksdb::DBCompressionType::None);
 
             match cf_name.as_str() {
                 CF_HEADERS | CF_BODIES => {
-                    cf_opts.set_compression_type(rocksdb::DBCompressionType::Zstd);
                     cf_opts.set_write_buffer_size(128 * 1024 * 1024); // 128MB
                     cf_opts.set_max_write_buffer_number(4);
                     cf_opts.set_target_file_size_base(256 * 1024 * 1024); // 256MB
@@ -252,7 +254,6 @@ impl Store {
                     cf_opts.set_block_based_table_factory(&block_opts);
                 }
                 CF_CANONICAL_BLOCK_HASHES | CF_BLOCK_NUMBERS => {
-                    cf_opts.set_compression_type(rocksdb::DBCompressionType::Lz4);
                     cf_opts.set_write_buffer_size(64 * 1024 * 1024); // 64MB
                     cf_opts.set_max_write_buffer_number(3);
                     cf_opts.set_target_file_size_base(128 * 1024 * 1024); // 128MB
@@ -263,7 +264,18 @@ impl Store {
                     cf_opts.set_block_based_table_factory(&block_opts);
                 }
                 CF_TRIE_NODES => {
-                    cf_opts.set_compression_type(rocksdb::DBCompressionType::Lz4);
+                    cf_opts.set_write_buffer_size(512 * 1024 * 1024); // 512MB
+                    cf_opts.set_max_write_buffer_number(6);
+                    cf_opts.set_min_write_buffer_number_to_merge(2);
+                    cf_opts.set_target_file_size_base(256 * 1024 * 1024); // 256MB
+                    cf_opts.set_memtable_prefix_bloom_ratio(0.2); // Bloom filter
+
+                    let mut block_opts = BlockBasedOptions::default();
+                    block_opts.set_block_size(16 * 1024); // 16KB
+                    block_opts.set_bloom_filter(10.0, false); // 10 bits per key
+                    cf_opts.set_block_based_table_factory(&block_opts);
+                }
+                CF_FLATKEYVALUE => {
                     cf_opts.set_write_buffer_size(512 * 1024 * 1024); // 512MB
                     cf_opts.set_max_write_buffer_number(6);
                     cf_opts.set_min_write_buffer_number_to_merge(2);
@@ -276,7 +288,6 @@ impl Store {
                     cf_opts.set_block_based_table_factory(&block_opts);
                 }
                 CF_RECEIPTS | CF_ACCOUNT_CODES => {
-                    cf_opts.set_compression_type(rocksdb::DBCompressionType::Lz4);
                     cf_opts.set_write_buffer_size(128 * 1024 * 1024); // 128MB
                     cf_opts.set_max_write_buffer_number(3);
                     cf_opts.set_target_file_size_base(256 * 1024 * 1024); // 256MB
@@ -287,7 +298,6 @@ impl Store {
                 }
                 _ => {
                     // Default for other CFs
-                    cf_opts.set_compression_type(rocksdb::DBCompressionType::Lz4);
                     cf_opts.set_write_buffer_size(64 * 1024 * 1024); // 64MB
                     cf_opts.set_max_write_buffer_number(3);
                     cf_opts.set_target_file_size_base(128 * 1024 * 1024); // 128MB