diff --git a/src/library.js b/src/library.js
index cc9d3f69fcde3..135c734fc0aa6 100644
--- a/src/library.js
+++ b/src/library.js
@@ -2911,7 +2911,7 @@ addToLibrary({
       // code paths as similar as possible on both sides.)
       // -1 - code is the encoding of a proxied EM_ASM, as a negative number
       // (positive numbers are non-EM_ASM calls).
-      return proxyToMainThread.apply(null, [-1 - code, sync].concat(args));
+      return proxyToMainThread(-1 - code, sync, ...args);
     }
 #endif
 #if ASSERTIONS
diff --git a/src/library_pthread.js b/src/library_pthread.js
index a204c2b5b3b90..bc65dd9249f4b 100644
--- a/src/library_pthread.js
+++ b/src/library_pthread.js
@@ -957,21 +957,17 @@ var LibraryPThread = {
 #if MEMORY64
   // Calls proxyToMainThread but returns a bigint rather than a number
   $proxyToMainThreadPtr__deps: ['$proxyToMainThread'],
-  $proxyToMainThreadPtr: function() {
-    return BigInt(proxyToMainThread.apply(null, arguments));
-  },
+  $proxyToMainThreadPtr: (...args) => BigInt(proxyToMainThread(...args)),
 #endif
 
   $proxyToMainThread__deps: ['$withStackSave', '_emscripten_run_on_main_thread_js'].concat(i53ConversionDeps),
-  $proxyToMainThread__docs: '/** @type{function(number, (number|boolean), ...(number|boolean))} */',
-  $proxyToMainThread: function(index, sync) {
+  $proxyToMainThread__docs: '/** @type{function(number, (number|boolean), ...number)} */',
+  $proxyToMainThread: (index, sync, ...callArgs) => {
     // Additional arguments are passed after those two, which are the actual
     // function arguments.
     // The serialization buffer contains the number of call params, and then
     // all the args here.
     // We also pass 'sync' to C separately, since C needs to look at it.
-    var numCallArgs = arguments.length - 2;
-    var outerArgs = arguments;
     // Allocate a buffer, which will be copied by the C code.
     return withStackSave(() => {
       // First passed parameter specifies the number of arguments to the function.
@@ -980,11 +976,11 @@ var LibraryPThread = {
       // type info here). To do that, add a "prefix" before each value that
       // indicates if it is a BigInt, which effectively doubles the number of
       // values we serialize for proxying. TODO: pack this?
-      var serializedNumCallArgs = numCallArgs {{{ WASM_BIGINT ? "* 2" : "" }}};
+      var serializedNumCallArgs = callArgs.length {{{ WASM_BIGINT ? "* 2" : "" }}};
       var args = stackAlloc(serializedNumCallArgs * 8);
       var b = {{{ getHeapOffset('args', 'i64') }}};
-      for (var i = 0; i < numCallArgs; i++) {
-        var arg = outerArgs[2 + i];
+      for (var i = 0; i < callArgs.length; i++) {
+        var arg = callArgs[i];
 #if WASM_BIGINT
         if (typeof arg == 'bigint') {
           // The prefix is non-zero to indicate a bigint.
diff --git a/test/other/metadce/test_metadce_minimal_pthreads.gzsize b/test/other/metadce/test_metadce_minimal_pthreads.gzsize
index d05eeed63c5c3..b1feb95664247 100644
--- a/test/other/metadce/test_metadce_minimal_pthreads.gzsize
+++ b/test/other/metadce/test_metadce_minimal_pthreads.gzsize
@@ -1 +1 @@
-4923
+4920
diff --git a/test/other/metadce/test_metadce_minimal_pthreads.jssize b/test/other/metadce/test_metadce_minimal_pthreads.jssize
index 67700c91ca4af..34e006b941803 100644
--- a/test/other/metadce/test_metadce_minimal_pthreads.jssize
+++ b/test/other/metadce/test_metadce_minimal_pthreads.jssize
@@ -1 +1 @@
-13664
+13635