diff --git a/easybuild/framework/easyblock.py b/easybuild/framework/easyblock.py
index 38fb3b0e7b..50482137c0 100644
--- a/easybuild/framework/easyblock.py
+++ b/easybuild/framework/easyblock.py
@@ -3395,6 +3395,14 @@ def sanity_check_rpath(self, rpath_dirs=None, check_readelf_rpath=True):
                 self.log.debug(f"Sanity checking RPATH for files in {dirpath}")
 
                 for path in [os.path.join(dirpath, x) for x in os.listdir(dirpath)]:
+                    # skip the check for any symlinks that resolve to outside the installation directory
+                    if not is_parent_path(self.installdir, path):
+                        realpath = os.path.realpath(path)
+                        msg = (f"Skipping RPATH sanity check for {path}, since its absolute path {realpath} resolves to"
+                               f" outside the installation directory {self.installdir}")
+                        self.log.info(msg)
+                        continue
+
                     self.log.debug(f"Sanity checking RPATH for {path}")
 
                     out = get_linked_libs_raw(path)