diff --git a/easybuild/easyconfigs/q/QEMU/QEMU-10.1.0-GCCcore-14.3.0.eb b/easybuild/easyconfigs/q/QEMU/QEMU-10.1.0-GCCcore-14.3.0.eb
new file mode 100644
index 00000000000..1d790f2f958
--- /dev/null
+++ b/easybuild/easyconfigs/q/QEMU/QEMU-10.1.0-GCCcore-14.3.0.eb
@@ -0,0 +1,135 @@
+name = 'QEMU'
+version = '10.1.0'
+
+homepage = 'https://www.qemu.org'
+description = """A generic and open source machine emulator and virtualizer"""
+
+toolchain = {'name': 'GCCcore', 'version': '14.3.0'}
+
+source_urls = ['https://download.qemu.org']
+sources = [SOURCELOWER_TAR_XZ]
+checksums = ['e0517349b50ca73ebec2fa85b06050d5c463ca65c738833bd8fc1f15f180be51']
+
+builddependencies = [
+    ('binutils', '2.44'),
+    ('Meson', '1.8.2'),
+    ('Ninja', '1.13.0'),
+    ('pkgconf', '2.4.3'),
+    ('flex', '2.6.4'),
+    ('Bison', '3.8.2'),
+]
+
+dependencies = [
+    # User interface
+    ('X11', '20250608'),
+    ('DBus', '1.16.2'),
+    ('pixman', '0.46.4'),
+    ('SDL2', '2.32.10'),
+    ('SDL2_image', '2.8.8'),
+    ('GTK3', '3.24.43'),
+    ('libpng', '1.6.50'),
+    ('ncurses', '6.5'),
+    # Audio
+    ('alsa-lib', '1.2.14'),
+    # Crypto (GnuTLS, gnupg-bundle, or nettle)
+    ('GnuTLS', '3.8.10'),
+    # Optional dependencies
+    ('Python', '3.13.5'),
+    ('numactl', '2.0.19'),
+    ('liburing', '2.12'),
+    ('libaio', '0.3.113'),
+    ('GDB', '16.3'),
+    ('elfutils', '0.193'),
+    ('Capstone', '5.0.6'),
+    ('dtc', '1.7.2'),
+    ('libslirp', '4.9.1'),
+    ('liburing', '2.12'),
+    ('FUSE', '3.17.4'),
+    ('alsa-lib', '1.2.14'),
+    ('GLib', '2.85.3'),
+    ('libtasn1', '4.20.0'),
+    ('libiconv', '1.18'),
+    ('cURL', '8.14.1'),
+    ('libepoxy', '1.5.10'),
+    ('LZO', '2.10'),
+    ('snappy', '1.2.2'),
+    ('bzip2', '1.0.8'),
+    ('zstd', '1.5.7'),
+]
+
+# List of emulation targets to build, leave empty to build all
+# targets = [
+#     'aarch64-linux-user',
+#     'aarch64_be-linux-user',
+#     'alpha-linux-user',
+#     'arm-linux-user',
+#     'armeb-linux-user',
+#     'hexagon-linux-user',
+#     'hppa-linux-user',
+#     'i386-linux-user',
+#     'loongarch64-linux-user',
+#     'm68k-linux-user',
+#     'microblaze-linux-user',
+#     'microblazeel-linux-user',
+#     'mips-linux-user',
+#     'mips64-linux-user',
+#     'mips64el-linux-user',
+#     'mipsel-linux-user',
+#     'mipsn32-linux-user',
+#     'mipsn32el-linux-user',
+#     'or1k-linux-user',
+#     'ppc-linux-user',
+#     'ppc64-linux-user',
+#     'ppc64le-linux-user',
+#     'riscv32-linux-user',
+#     'riscv64-linux-user',
+#     's390x-linux-user',
+#     'sh4-linux-user',
+#     'sh4eb-linux-user',
+#     'sparc-linux-user',
+#     'sparc32plus-linux-user',
+#     'sparc64-linux-user',
+#     'x86_64-linux-user',
+#     'xtensa-linux-user',
+#     'xtensaeb-linux-user',
+#     'aarch64-softmmu',
+#     'alpha-softmmu',
+#     'arm-softmmu',
+#     'avr-softmmu',
+#     'hppa-softmmu',
+#     'i386-softmmu',
+#     'loongarch64-softmmu',
+#     'm68k-softmmu',
+#     'microblaze-softmmu',
+#     'microblazeel-softmmu',
+#     'mips-softmmu',
+#     'mips64-softmmu',
+#     'mips64el-softmmu',
+#     'mipsel-softmmu',
+#     'or1k-softmmu',
+#     'ppc-softmmu',
+#     'ppc64-softmmu',
+#     'riscv32-softmmu',
+#     'riscv64-softmmu',
+#     'rx-softmmu',
+#     's390x-softmmu',
+#     'sh4-softmmu',
+#     'sh4eb-softmmu',
+#     'sparc-softmmu',
+#     'sparc64-softmmu',
+#     'tricore-softmmu',
+#     'x86_64-softmmu',
+#     'xtensa-softmmu',
+#     'xtensaeb-softmmu',
+# ]
+
+# QEMU linker uses response files which circumvent EB rpath wrapper, but QEMU uses RUNPATH by default
+check_readelf_rpath = False
+
+# Binaries depend on what targts to build
+sanity_check_paths = {
+    'files': ['include/qemu-plugin.h'],
+    'dirs': ['bin'],
+}
+
+moduleclass = 'tools'