diff --git a/src/coreclr/vm/classlayoutinfo.cpp b/src/coreclr/vm/classlayoutinfo.cpp
index bdef0e40596f34..612c119be79f01 100644
--- a/src/coreclr/vm/classlayoutinfo.cpp
+++ b/src/coreclr/vm/classlayoutinfo.cpp
@@ -612,7 +612,7 @@ VOID EEClassLayoutInfo::CollectLayoutFieldMetadataThrowing(
     pEEClassLayoutInfoOut->m_cbPackingSize = packingSize;
 
     BOOL fParentHasLayout = pParentMT && pParentMT->HasLayout();
-    UINT32 cbAdjustedParentLayoutNativeSize = 0;
+    UINT32 cbAdjustedParentLayoutSize = 0;
     EEClassLayoutInfo *pParentLayoutInfo = NULL;
     if (fParentHasLayout)
     {
@@ -622,11 +622,11 @@ VOID EEClassLayoutInfo::CollectLayoutFieldMetadataThrowing(
         // got bumped up to a size of 1 for compatibility reasons, then
         // we need to remove the padding, but ONLY for inheritance situations.
         if (pParentLayoutInfo->IsZeroSized()) {
-            cbAdjustedParentLayoutNativeSize = 0;
+            cbAdjustedParentLayoutSize = 0;
         }
         else
         {
-            cbAdjustedParentLayoutNativeSize = pParentMT->GetNumInstanceFieldBytes();
+            cbAdjustedParentLayoutSize = pParentMT->GetNumInstanceFieldBytes();
         }
     }
 
@@ -668,7 +668,7 @@ VOID EEClassLayoutInfo::CollectLayoutFieldMetadataThrowing(
     }
     CQuickArray<LayoutRawFieldInfo*> pSortArray;
     pSortArray.ReSizeThrows(cbSortArraySize.Value());
-    SetOffsetsAndSortFields(pInternalImport, cl, pInfoArrayOut, cInstanceFields, fExplicitOffsets, cbAdjustedParentLayoutNativeSize, pModule, pSortArray.Ptr());
+    SetOffsetsAndSortFields(pInternalImport, cl, pInfoArrayOut, cInstanceFields, fExplicitOffsets, cbAdjustedParentLayoutSize, pModule, pSortArray.Ptr());
 
     ULONG classSizeInMetadata = 0;
     if (FAILED(pInternalImport->GetClassTotalSize(cl, &classSizeInMetadata)))
@@ -690,14 +690,13 @@ VOID EEClassLayoutInfo::CollectLayoutFieldMetadataThrowing(
     }
 
     BYTE parentManagedAlignmentRequirement = 0;
-    UINT32 parentSize = pParentMT->GetNumInstanceFieldBytes();
     if (pParentMT && (pParentMT->IsManagedSequential() || (pParentMT->GetClass()->HasExplicitFieldOffsetLayout() && pParentMT->IsBlittable())))
     {
         parentManagedAlignmentRequirement = pParentLayoutInfo->m_ManagedLargestAlignmentRequirementOfAllMembers;
     }
 
     CalculateSizeAndFieldOffsets(
-        parentSize,
+        cbAdjustedParentLayoutSize,
         cInstanceFields,
         fExplicitOffsets,
         pSortArray.Ptr(),
diff --git a/src/tests/Interop/LayoutClass/LayoutClassTest.cs b/src/tests/Interop/LayoutClass/LayoutClassTest.cs
index d87be9e81c3955..2181bb30528d44 100644
--- a/src/tests/Interop/LayoutClass/LayoutClassTest.cs
+++ b/src/tests/Interop/LayoutClass/LayoutClassTest.cs
@@ -12,6 +12,11 @@ public class EmptyBase
     {
     }
 
+    [StructLayout(LayoutKind.Sequential)]
+    public class EmptyBase2 : EmptyBase
+    {
+    }
+
     [StructLayout(LayoutKind.Sequential)]
     public class SeqDerivedClass : EmptyBase
     {
@@ -23,6 +28,17 @@ public SeqDerivedClass(int _a)
         }
     }
 
+    [StructLayout(LayoutKind.Sequential)]
+    public class SeqDerivedClass2 : EmptyBase2
+    {
+        public int a;
+
+        public SeqDerivedClass2(int _a)
+        {
+            a = _a;
+        }
+    }
+
     [StructLayout(LayoutKind.Sequential)]
     public sealed class SeqClass
     {
@@ -185,8 +201,8 @@ public static void DerivedClassWithEmptyBase()
             Console.WriteLine($"Running {nameof(DerivedClassWithEmptyBase)}...");
 
             string s = "before";
-            var p = new SeqDerivedClass(42);
-            Assert.IsTrue(DerivedSeqLayoutClassByRef(p, 42));
+            Assert.IsTrue(DerivedSeqLayoutClassByRef(new SeqDerivedClass(42), 42));
+            Assert.IsTrue(DerivedSeqLayoutClassByRef(new SeqDerivedClass2(42), 42));
         }
 
         public static void ExplicitClass()