diff --git a/src/c/config/discover.ml b/src/c/config/discover.ml
new file mode 100644
index 00000000..ea0c3d4c
--- /dev/null
+++ b/src/c/config/discover.ml
@@ -0,0 +1,139 @@
+module C = Configurator.V1
+
+(** [uppercase_ascii] is equivalent to OCaml 4.03+; works on OCaml 4.02.0 *)
+let uppercase_ascii s =
+  let b_uppercase_ascii s = Bytes.map Char.uppercase_ascii s in
+  b_uppercase_ascii (Bytes.of_string s) |> Bytes.to_string
+
+let use_system_libuv =
+  match Sys.getenv "LUV_USE_SYSTEM_LIBUV" with
+  | "yes" -> true
+  | _ -> false
+  | exception Not_found -> false
+
+(** [system_libuv_flags kind context_name] gets the value of the environment
+    variable ["LUV_${kind}_LIBUV_${uppercase(sanitize(context_name))}"].
+
+    For example, if [kind] is ["lib"] and [context_name] is ["default.android_aarch64"]
+    then the result would be the value of the environment variable
+    ["LUV_LIB_LIBUV_DEFAULT_ANDROID_AARCH64"]. *)
+let system_libuv_flags ~kind ~context_name =
+  let normalized_context_name =
+    Str.(global_replace (regexp "[^A-Z0-9]") "_" (uppercase_ascii context_name))
+  in
+  let envvar_name =
+    "LUV_" ^ uppercase_ascii kind ^ "_LIBUV_" ^ normalized_context_name
+  in
+  match Sys.getenv envvar_name with
+  | value -> Some value
+  | exception Not_found -> None
+
+(** [split_on_semicolons s] splits a semi-colon separated string [s] *)
+let split_on_semicolons s = Str.(split (regexp ";+") s)
+
+(** [uv_lib ~context_name] gets the linker flags to link libuv.
+
+    When the environment variable ["LUV_USE_SYSTEM_LIBUV"] is not ["yes"], there
+    will be no linker flags.
+
+    When the environment variable defined by [system_libuv_flags ~kind:"lib"] is non-empty, then
+    those flags will be split by semicolons and used with all empty flags removed.
+
+    Otherwise the default linker flags are [["-luv"]].
+
+    In particular, if ["LUV_USE_SYSTEM_LIBUV"] is ["yes"] and
+    [context_name] is ["default.windows"] then:
+
+    * ["LUV_LIB_LIBUV_DEFAULT_WINDOWS"]=[""]  -> [["-luv"]]
+    * ["LUV_LIB_LIBUV_DEFAULT_WINDOWS"]=[";"] -> [[]]
+    * ["LUV_LIB_LIBUV_DEFAULT_WINDOWS"]=["-L/usr/lib;-llibuv"] -> [["-L/usr/lib"; "-llibuv"]]
+    * ["LUV_LIB_LIBUV_DEFAULT_WINDOWS"]=[";-llibuv"] -> [["-llibuv"]]
+
+    In the above rules, an undefined environment variable and an empty environment
+    variable are treated the same. *)
+let uv_lib ~context_name =
+  match (use_system_libuv, system_libuv_flags ~kind:"lib" ~context_name) with
+  | false, _ -> []
+  | true, Some flags when flags <> "" ->
+      split_on_semicolons flags |> List.filter (fun i -> i <> "")
+  | true, Some _ | true, None -> [ "-luv" ]
+
+(** [uv_include ~context_name ~vendor_dir] gets the compiler flags to include compile libuv consuming code.
+
+    ctypes and stdlib headers are always included.
+
+    When the environment variable ["LUV_USE_SYSTEM_LIBUV"] is not ["yes"], there
+    will be extra include flags: -I vendor/libuv/include
+
+    When the environment variable defined by [system_libuv_flags ~kind:"include"] is non-empty, then
+    those include flags will be split by semicolons and used with all empty flags removed.
+
+    Otherwise there are no extra include flags.
+
+    See [uv_lib] for how the semicolon splitting works. For example:
+
+    * ["LUV_INCLUDE_LIBUV_DEFAULT_WINDOWS"]=["-I;C:\\Program Files\\include"] -> [["-I"; "C:\\Program Files\\include"]] *)
+let uv_include ~context_name ~vendor_dir =
+  match
+    (use_system_libuv, system_libuv_flags ~kind:"include" ~context_name)
+  with
+  | false, _ -> ["-I"; Filename.concat vendor_dir "include"]
+  | true, Some flags when flags <> "" ->
+      split_on_semicolons flags
+      |> List.filter (fun s -> s <> "")
+  | true, Some _ | true, None -> []
+
+(** [compile_c ~context_name ~vendor_dir] is the contents of a portable shell script that compiles C code.
+
+    The usage for the shell script is:
+    {v
+      compile_c.sh C_SOURCE_FILE INCLUDEDIR_CTYPES TARGET CC CFLAGS
+    v}
+
+    The TARGET is the destination executable file.
+
+    The CC and CFLAGS can be the %{cc} compiler and flags from
+    https://dune.readthedocs.io/en/stable/concepts.html#flags
+
+    The shell script will include the [uv_include] flags. *)
+let compile_c c ~context_name ~vendor_dir =
+  let oflag =
+    match C.ocaml_config_var c "ccomp_type" with
+    | Some "msvc" -> "/Fe"
+    | _ -> "-o "
+  in
+  let stdlib_where = C.ocaml_config_var_exn c "standard_library" in
+  let extra_flags =
+    uv_include ~context_name ~vendor_dir
+    |> List.map (fun s -> "\"" ^ String.escaped s ^ "\"")
+    |> String.concat " "
+  in
+  Format.sprintf "\
+#!/bin/sh
+# context=%s
+set -euf
+src=$1; shift
+ctypes=$1; shift
+target=$1; shift
+\"$@\" \"$src\" -I \"$ctypes\" -I \"%s\" %s %s\"$target\"
+" context_name stdlib_where extra_flags oflag
+
+let () =
+  let context_name = ref "default" in
+  let vendor_dir =
+    ref
+      Filename.(concat (concat (concat (Sys.getcwd ()) "..") "vendor") "libuv")
+  in
+  C.main
+    ~args:[ 
+      ("-context", Arg.String (fun s -> context_name := s), "Dune context");
+      ("-vendor-dir", Arg.String (fun s -> vendor_dir := s), "Absolute path to vendor/libuv");
+    ]
+    ~name:""
+    (fun c ->
+      C.Flags.write_sexp "uv_lib.sexp" (uv_lib ~context_name:!context_name);
+      C.Flags.write_sexp "uv_include.sexp" (uv_include ~context_name:!context_name ~vendor_dir:!vendor_dir);
+      (* binary mode so Windows does not use CRLF *)
+      let oc = open_out_bin "compile_c.sh" in
+      output_string oc (compile_c c ~context_name:!context_name ~vendor_dir:!vendor_dir);
+      close_out oc)
diff --git a/src/c/config/dune b/src/c/config/dune
new file mode 100644
index 00000000..d1a57ca1
--- /dev/null
+++ b/src/c/config/dune
@@ -0,0 +1,12 @@
+(executable
+ (name discover)
+ (libraries dune-configurator str))
+
+(rule
+ (targets uv_lib.sexp uv_include.sexp compile_c.sh)
+ (deps
+  (env_var LUV_USE_SYSTEM_LIBUV)
+  (env_var LUV_LIB_LIBUV_DEFAULT)
+  (env_var LUV_INCLUDE_LIBUV_DEFAULT))
+ (action
+  (run ./discover.exe -context %{context_name})))
diff --git a/src/c/dune b/src/c/dune
index ab3f9e93..202231b8 100644
--- a/src/c/dune
+++ b/src/c/dune
@@ -1,6 +1,6 @@
 (* -*- tuareg -*- *)
 
-let foreign_archives, uv_library_flag, include_dirs, i_option, install_h =
+let foreign_archives, include_dirs, install_h =
   let use_system_libuv =
     match Sys.getenv "LUV_USE_SYSTEM_LIBUV" with
     | "yes" -> true
@@ -9,16 +9,12 @@ let foreign_archives, uv_library_flag, include_dirs, i_option, install_h =
   in
 
   if use_system_libuv then
-    "",
-    "-luv",
     "",
     "",
     false
   else
     "(foreign_archives uv)",
-    "",
     "(include_dirs vendor/libuv/include)",
-    "-I vendor/libuv/include",
     true
 
 let () = Jbuild_plugin.V1.send @@ {|
@@ -33,9 +29,10 @@ let () = Jbuild_plugin.V1.send @@ {|
  (foreign_stubs
   (language c)
   (names c_generated_functions helpers)
+  (flags :standard (:include config/uv_include.sexp))
   |}^ include_dirs ^{|)
  |}^ foreign_archives ^{|
- (c_library_flags |}^ uv_library_flag ^{| (:include extra_libs.sexp)))
+ (c_library_flags (:include config/uv_lib.sexp) (:include extra_libs.sexp)))
 
 |}^ (if not install_h then "" else {|
 
@@ -119,20 +116,9 @@ let () = Jbuild_plugin.V1.send @@ {|
 ; Based partially on
 ;   https://github.com/avsm/ocaml-yaml/blob/master/types/stubgen/jbuild#L20
 (rule
- (targets generate_types_step_2.exe)
- (deps (:c generate_types_step_2.c) helpers.h shims.h)
- (action (bash "\
-  if [ '%{ocaml-config:ccomp_type}' = 'msvc' ]; then \
-    %{cc} %{c} \
-    -I '%{lib:ctypes:.}' \
-    -I %{ocaml_where} \
-    |}^ i_option ^{| /Fe\"%{targets}\"; \
-  else \
-    %{cc} %{c} \
-    -I '%{lib:ctypes:.}' \
-    -I %{ocaml_where} \
-    |}^ i_option ^{| -o %{targets}; \
-  fi")))
+ (target generate_types_step_2.exe)
+ (deps (:c generate_types_step_2.c) (:compile_c config/compile_c.sh) helpers.h shims.h)
+ (action (run bash %{compile_c} "%{c}" "%{lib:ctypes:.}" "%{target}" %{cc})))
 
 (rule
  (with-stdout-to luv_c_generated_types.ml
diff --git a/src/unix/dune b/src/unix/dune
index 9e7fe97d..d37cb8c6 100644
--- a/src/unix/dune
+++ b/src/unix/dune
@@ -1,5 +1,5 @@
 (library
  (public_name luv_unix)
  (libraries luv luv.c result unix)
- (foreign_stubs (language c) (names luv_unix))
+ (foreign_stubs (language c) (names luv_unix) (flags :standard (:include ../c/config/uv_include.sexp)))
  (flags (:standard -w -49 -open Result)))
diff --git a/test/headers/dune b/test/headers/dune
index c0ffddf1..dc819f79 100644
--- a/test/headers/dune
+++ b/test/headers/dune
@@ -1,4 +1,4 @@
 (executable
  (name headers)
  (libraries luv)
- (foreign_stubs (language c) (names headers)))
+ (foreign_stubs (language c) (names headers) (flags :standard (:include ../../src/c/config/uv_include.sexp))))