diff --git a/appengine/flexible/pubsub/requirements.txt b/appengine/flexible/pubsub/requirements.txt
index 69777af95d9..b1c0a2f66d8 100644
--- a/appengine/flexible/pubsub/requirements.txt
+++ b/appengine/flexible/pubsub/requirements.txt
@@ -1,3 +1,3 @@
 Flask==1.1.2
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
 gunicorn==20.0.4
diff --git a/appengine/standard_python3/pubsub/requirements.txt b/appengine/standard_python3/pubsub/requirements.txt
index 0c4a124a4eb..f787f62ee6c 100644
--- a/appengine/standard_python3/pubsub/requirements.txt
+++ b/appengine/standard_python3/pubsub/requirements.txt
@@ -1,4 +1,4 @@
 Flask==1.1.2
 google-api-python-client==1.9.3
 google-auth==1.18.0
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
diff --git a/appengine/standard_python37/pubsub/requirements.txt b/appengine/standard_python37/pubsub/requirements.txt
index 0c4a124a4eb..f787f62ee6c 100644
--- a/appengine/standard_python37/pubsub/requirements.txt
+++ b/appengine/standard_python37/pubsub/requirements.txt
@@ -1,4 +1,4 @@
 Flask==1.1.2
 google-api-python-client==1.9.3
 google-auth==1.18.0
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
diff --git a/asset/cloud-client/requirements.txt b/asset/cloud-client/requirements.txt
index 08166568ef9..258cb352943 100644
--- a/asset/cloud-client/requirements.txt
+++ b/asset/cloud-client/requirements.txt
@@ -1,5 +1,5 @@
 google-cloud-storage==1.29.0
 google-cloud-asset==1.1.0
 google-cloud-resource-manager==0.30.2
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
 google-cloud-bigquery==1.25.0
diff --git a/container_registry/container_analysis/requirements.txt b/container_registry/container_analysis/requirements.txt
index 4fa09a775c6..1ed23cb0f54 100644
--- a/container_registry/container_analysis/requirements.txt
+++ b/container_registry/container_analysis/requirements.txt
@@ -1,4 +1,4 @@
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
 google-cloud-containeranalysis==0.3.1
 grafeas==0.4.0
 pytest==5.3.0; python_version > "3.0"
diff --git a/dlp/requirements.txt b/dlp/requirements.txt
index 0cbd7e0a0b5..cf3b84f38fe 100644
--- a/dlp/requirements.txt
+++ b/dlp/requirements.txt
@@ -1,5 +1,5 @@
 google-cloud-dlp==1.0.0
 google-cloud-storage==1.29.0
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
 google-cloud-datastore==1.12.0
 google-cloud-bigquery==1.25.0
diff --git a/functions/ocr/app/requirements.txt b/functions/ocr/app/requirements.txt
index 38f7aeb5468..7a36dc89061 100644
--- a/functions/ocr/app/requirements.txt
+++ b/functions/ocr/app/requirements.txt
@@ -1,4 +1,4 @@
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
 google-cloud-storage==1.29.0
 google-cloud-translate==2.0.1
 google-cloud-vision==1.0.0
diff --git a/functions/pubsub/requirements.txt b/functions/pubsub/requirements.txt
index 98dab2bec2c..cde8d3d8427 100644
--- a/functions/pubsub/requirements.txt
+++ b/functions/pubsub/requirements.txt
@@ -1 +1 @@
-google-cloud-pubsub==1.5.0
\ No newline at end of file
+google-cloud-pubsub==1.6.0
\ No newline at end of file
diff --git a/functions/tips/requirements.txt b/functions/tips/requirements.txt
index 27e7fdcecb3..19579a9649e 100644
--- a/functions/tips/requirements.txt
+++ b/functions/tips/requirements.txt
@@ -1,5 +1,5 @@
 google-cloud-error-reporting==0.34.0
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
 python-dateutil==2.8.1
 requests==2.24.0
 xmltodict==0.12.0
diff --git a/healthcare/api-client/dicom/requirements.txt b/healthcare/api-client/dicom/requirements.txt
index b3d9a51f72b..b53c10a190a 100644
--- a/healthcare/api-client/dicom/requirements.txt
+++ b/healthcare/api-client/dicom/requirements.txt
@@ -1,5 +1,5 @@
 google-api-python-client==1.9.3
 google-auth-httplib2==0.0.3
 google-auth==1.18.0
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
 requests==2.24.0
diff --git a/healthcare/api-client/v1/dicom/requirements.txt b/healthcare/api-client/v1/dicom/requirements.txt
index b3d9a51f72b..b53c10a190a 100644
--- a/healthcare/api-client/v1/dicom/requirements.txt
+++ b/healthcare/api-client/v1/dicom/requirements.txt
@@ -1,5 +1,5 @@
 google-api-python-client==1.9.3
 google-auth-httplib2==0.0.3
 google-auth==1.18.0
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
 requests==2.24.0
diff --git a/iot/api-client/end_to_end_example/requirements.txt b/iot/api-client/end_to_end_example/requirements.txt
index f2de810d60f..5a92c00c366 100644
--- a/iot/api-client/end_to_end_example/requirements.txt
+++ b/iot/api-client/end_to_end_example/requirements.txt
@@ -2,6 +2,6 @@ cryptography==2.9.2
 google-api-python-client==1.9.3
 google-auth-httplib2==0.0.3
 google-auth==1.18.0
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
 pyjwt==1.7.1
 paho-mqtt==1.5.0
diff --git a/iot/api-client/gcs_file_to_device/requirements.txt b/iot/api-client/gcs_file_to_device/requirements.txt
index a7246715f90..494cf634e51 100644
--- a/iot/api-client/gcs_file_to_device/requirements.txt
+++ b/iot/api-client/gcs_file_to_device/requirements.txt
@@ -2,7 +2,7 @@ google-api-python-client==1.9.3
 google-auth==1.18.0
 google-auth-httplib2==0.0.3
 google-cloud-iot==1.0.0
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
 google-cloud-storage==1.29.0
 cryptography==2.9.2
 paho-mqtt==1.5.0
diff --git a/iot/api-client/http_example/requirements.txt b/iot/api-client/http_example/requirements.txt
index f5f8083b556..9a643300472 100644
--- a/iot/api-client/http_example/requirements.txt
+++ b/iot/api-client/http_example/requirements.txt
@@ -3,6 +3,6 @@ google-api-python-client==1.9.3
 google-auth-httplib2==0.0.3
 google-auth==1.18.0
 google-cloud-iot==1.0.0
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
 pyjwt==1.7.1
 requests==2.24.0
diff --git a/iot/api-client/manager/requirements.txt b/iot/api-client/manager/requirements.txt
index 39e5a46038e..a989ac8c597 100644
--- a/iot/api-client/manager/requirements.txt
+++ b/iot/api-client/manager/requirements.txt
@@ -4,6 +4,6 @@ google-api-python-client==1.9.3
 google-auth-httplib2==0.0.3
 google-auth==1.18.0
 google-cloud-iot==1.0.0
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
 paho-mqtt==1.5.0
 pyjwt==1.7.1
diff --git a/iot/api-client/mqtt_example/requirements.txt b/iot/api-client/mqtt_example/requirements.txt
index 7401a7ba2da..b1a2f7e8758 100644
--- a/iot/api-client/mqtt_example/requirements.txt
+++ b/iot/api-client/mqtt_example/requirements.txt
@@ -2,7 +2,7 @@ cryptography==2.9.2
 google-api-python-client==1.9.3
 google-auth-httplib2==0.0.3
 google-auth==1.18.0
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
 google-cloud-iot==1.0.0
 grpc-google-iam-v1==0.12.3
 pyjwt==1.7.1
diff --git a/iot/api-client/scripts/requirements.txt b/iot/api-client/scripts/requirements.txt
index 9cc17af84c3..9b496510abb 100644
--- a/iot/api-client/scripts/requirements.txt
+++ b/iot/api-client/scripts/requirements.txt
@@ -1 +1 @@
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
diff --git a/pubsub/cloud-client/requirements.txt b/pubsub/cloud-client/requirements.txt
index 9cc17af84c3..9b496510abb 100644
--- a/pubsub/cloud-client/requirements.txt
+++ b/pubsub/cloud-client/requirements.txt
@@ -1 +1 @@
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
diff --git a/storage/cloud-client/requirements.txt b/storage/cloud-client/requirements.txt
index b4b349361da..12d2e64e057 100644
--- a/storage/cloud-client/requirements.txt
+++ b/storage/cloud-client/requirements.txt
@@ -1,2 +1,2 @@
-google-cloud-pubsub==1.5.0
+google-cloud-pubsub==1.6.0
 google-cloud-storage==1.29.0