diff --git a/appengine/flexible/pubsub/requirements.txt b/appengine/flexible/pubsub/requirements.txt
index 967df1c2c41..454c4814bb2 100644
--- a/appengine/flexible/pubsub/requirements.txt
+++ b/appengine/flexible/pubsub/requirements.txt
@@ -1,3 +1,3 @@
 Flask==1.1.2
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
 gunicorn==20.0.4
diff --git a/appengine/standard_python37/pubsub/requirements.txt b/appengine/standard_python37/pubsub/requirements.txt
index 5f7fce7b598..e8d158364fd 100644
--- a/appengine/standard_python37/pubsub/requirements.txt
+++ b/appengine/standard_python37/pubsub/requirements.txt
@@ -1,4 +1,4 @@
 Flask==1.1.2
 google-api-python-client==1.8.2
 google-auth==1.14.2
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
diff --git a/asset/cloud-client/requirements.txt b/asset/cloud-client/requirements.txt
index 8a0e6f8354e..fe80ee7fda1 100644
--- a/asset/cloud-client/requirements.txt
+++ b/asset/cloud-client/requirements.txt
@@ -1,4 +1,4 @@
 google-cloud-storage==1.28.0
 google-cloud-asset==0.10.0
 google-cloud-resource-manager==0.30.1
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
diff --git a/container_registry/container_analysis/requirements.txt b/container_registry/container_analysis/requirements.txt
index 98bceafbc5f..32e0defc4c2 100644
--- a/container_registry/container_analysis/requirements.txt
+++ b/container_registry/container_analysis/requirements.txt
@@ -1,4 +1,4 @@
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
 google-cloud-containeranalysis==0.3.1
 grafeas==0.1.0
 pytest==5.3.0; python_version > "3.0"
diff --git a/dlp/requirements.txt b/dlp/requirements.txt
index 0bd682d1524..77d629aff61 100644
--- a/dlp/requirements.txt
+++ b/dlp/requirements.txt
@@ -1,5 +1,5 @@
 google-cloud-dlp==0.14.0
 google-cloud-storage==1.28.0
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
 google-cloud-datastore==1.12.0
 google-cloud-bigquery==1.24.0
diff --git a/functions/ocr/app/requirements.txt b/functions/ocr/app/requirements.txt
index cb387fe8e68..dbb51984d20 100644
--- a/functions/ocr/app/requirements.txt
+++ b/functions/ocr/app/requirements.txt
@@ -1,4 +1,4 @@
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
 google-cloud-storage==1.28.0
 google-cloud-translate==2.0.1
 google-cloud-vision==1.0.0
diff --git a/functions/pubsub/requirements.txt b/functions/pubsub/requirements.txt
index d77820e6457..d9d8db069ea 100644
--- a/functions/pubsub/requirements.txt
+++ b/functions/pubsub/requirements.txt
@@ -1 +1 @@
-google-cloud-pubsub==1.4.2
\ No newline at end of file
+google-cloud-pubsub==1.4.3
\ No newline at end of file
diff --git a/functions/tips/requirements.txt b/functions/tips/requirements.txt
index c7db07f30d8..b4ecc158aeb 100644
--- a/functions/tips/requirements.txt
+++ b/functions/tips/requirements.txt
@@ -1,5 +1,5 @@
 google-cloud-error-reporting==0.33.0
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
 python-dateutil==2.8.1
 requests==2.23.0
 xmltodict==0.12.0
diff --git a/iot/api-client/end_to_end_example/requirements.txt b/iot/api-client/end_to_end_example/requirements.txt
index 93302a1da44..0df5e5aa6b2 100644
--- a/iot/api-client/end_to_end_example/requirements.txt
+++ b/iot/api-client/end_to_end_example/requirements.txt
@@ -2,6 +2,6 @@ cryptography==2.9.2
 google-api-python-client==1.8.2
 google-auth-httplib2==0.0.3
 google-auth==1.14.2
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
 pyjwt==1.7.1
-paho-mqtt==1.5.0
+paho-mqtt==1.5.0
\ No newline at end of file
diff --git a/iot/api-client/gcs_file_to_device/requirements.txt b/iot/api-client/gcs_file_to_device/requirements.txt
index dccf08e2a03..757b5c45af8 100644
--- a/iot/api-client/gcs_file_to_device/requirements.txt
+++ b/iot/api-client/gcs_file_to_device/requirements.txt
@@ -2,7 +2,7 @@ google-api-python-client==1.8.2
 google-auth==1.14.2
 google-auth-httplib2==0.0.3
 google-cloud-iot==1.0.0
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
 google-cloud-storage==1.28.0
 cryptography==2.9.2
 paho-mqtt==1.5.0
diff --git a/iot/api-client/http_example/requirements.txt b/iot/api-client/http_example/requirements.txt
index 09f1c99fcc8..7f55daf2aad 100644
--- a/iot/api-client/http_example/requirements.txt
+++ b/iot/api-client/http_example/requirements.txt
@@ -3,6 +3,6 @@ google-api-python-client==1.8.2
 google-auth-httplib2==0.0.3
 google-auth==1.14.2
 google-cloud-iot==1.0.0
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
 pyjwt==1.7.1
 requests==2.23.0
diff --git a/iot/api-client/manager/requirements.txt b/iot/api-client/manager/requirements.txt
index 15b1e891609..63856825bb3 100644
--- a/iot/api-client/manager/requirements.txt
+++ b/iot/api-client/manager/requirements.txt
@@ -4,6 +4,6 @@ google-api-python-client==1.8.2
 google-auth-httplib2==0.0.3
 google-auth==1.14.2
 google-cloud-iot==1.0.0
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
 paho-mqtt==1.5.0
 pyjwt==1.7.1
diff --git a/iot/api-client/mqtt_example/requirements.txt b/iot/api-client/mqtt_example/requirements.txt
index d102df469b4..f911c0de976 100644
--- a/iot/api-client/mqtt_example/requirements.txt
+++ b/iot/api-client/mqtt_example/requirements.txt
@@ -2,7 +2,7 @@ cryptography==2.9.2
 google-api-python-client==1.8.2
 google-auth-httplib2==0.0.3
 google-auth==1.14.2
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
 google-cloud-iot==1.0.0
 grpc-google-iam-v1==0.12.3
 pyjwt==1.7.1
diff --git a/iot/api-client/scripts/requirements.txt b/iot/api-client/scripts/requirements.txt
index fbfc0f4d395..110c3b79a33 100644
--- a/iot/api-client/scripts/requirements.txt
+++ b/iot/api-client/scripts/requirements.txt
@@ -1 +1 @@
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
diff --git a/pubsub/cloud-client/requirements.txt b/pubsub/cloud-client/requirements.txt
index fbfc0f4d395..110c3b79a33 100644
--- a/pubsub/cloud-client/requirements.txt
+++ b/pubsub/cloud-client/requirements.txt
@@ -1 +1 @@
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
diff --git a/storage/cloud-client/requirements.txt b/storage/cloud-client/requirements.txt
index 232a4848aa8..9aa4e8ddb50 100644
--- a/storage/cloud-client/requirements.txt
+++ b/storage/cloud-client/requirements.txt
@@ -1,2 +1,2 @@
-google-cloud-pubsub==1.4.2
+google-cloud-pubsub==1.4.3
 google-cloud-storage==1.28.0