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DESCRIPTION
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Package: TFBlearner
Title: Functionality for training TF-specific classifiers to predict TF bindings based on ATAC-seq data.
Version: 0.1.2
Authors@R:
person("Emanuel", "Sonder", , "emanuel.sonder@hest.ethz.ch", role = c("aut", "cre"),
comment = c(ORCID = "0000-0003-4788-9508"))
Description: Functionality for training TF-specific classifiers to predict TF bindings based on ATAC-seq data. Classifiers are trained using ChIP-seq peaks as ground truth for TF binding. Functions for compiling features, training and predicting are provided. For convenience all features and datasets used are contained within a MultiAssayExperiment object.
License: GPL-3
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2
Depends:
Matrix,
MultiAssayExperiment,
lightgbm,
data.table,
HDF5Array,
R (>= 3.5)
Imports:
BiocParallel,
Biostrings,
chromVAR,
DelayedMatrixStats,
DiceKriging,
GenomicAlignments,
GenomeInfoDb,
GenomicRanges,
GenomicScores,
Hmisc,
IRanges,
MatrixGenerics,
mlr3,
mlr3misc,
mlr3tuning,
mlr3learners,
mlr3mbo,
mlr3measures,
MotifDb,
motifmatchr,
paradox,
pdist,
R6,
ranger,
RcppML,
rgenoud,
Rsamtools,
rhdf5,
sparseMatrixStats,
S4Vectors,
preprocessCore,
PRROC,
SummarizedExperiment,
TFBSTools,
universalmotif
Suggests:
testthat (>= 3.0.0),
covr,
BSgenome.Hsapiens.UCSC.hg38,
phastCons100way.UCSC.hg38
Config/testthat/edition: 3
LazyData: true