diff --git a/tracer/build/_build/docker/smoke.dockerfile b/tracer/build/_build/docker/smoke.dockerfile
index b5162d5dc505..89352309d8b5 100644
--- a/tracer/build/_build/docker/smoke.dockerfile
+++ b/tracer/build/_build/docker/smoke.dockerfile
@@ -38,9 +38,6 @@ ENV DD_PROFILING_LOG_DIR=/var/log/datadog/dotnet
 
 ENV ASPNETCORE_URLS=http://localhost:5000
 
-# see https://github.com/dotnet/runtime/issues/77973
-ENV COMPlus_TieredCompilation=0
-
 # Copy the app across
 COPY --from=builder /src/publish /app/.
 
diff --git a/tracer/build/_build/docker/smoke.dotnet-tool.dockerfile b/tracer/build/_build/docker/smoke.dotnet-tool.dockerfile
index 58c422f69173..37c5d0255928 100644
--- a/tracer/build/_build/docker/smoke.dotnet-tool.dockerfile
+++ b/tracer/build/_build/docker/smoke.dotnet-tool.dockerfile
@@ -32,9 +32,6 @@ ENV DD_TRACE_DEBUG=1
 ENV ASPNETCORE_URLS=http://localhost:5000
 ENV DD_PROFILING_LOG_DIR=/var/log/datadog/dotnet
 
-# see https://github.com/dotnet/runtime/issues/77973
-ENV COMPlus_TieredCompilation=0
-
 # Copy the app across
 COPY --from=builder /src/publish /app/.
 
diff --git a/tracer/build/_build/docker/smoke.dotnet-tool.nuget.dockerfile b/tracer/build/_build/docker/smoke.dotnet-tool.nuget.dockerfile
index 631c6bb5b1d6..bfb6b78b5cd5 100644
--- a/tracer/build/_build/docker/smoke.dotnet-tool.nuget.dockerfile
+++ b/tracer/build/_build/docker/smoke.dotnet-tool.nuget.dockerfile
@@ -32,9 +32,6 @@ ENV DD_TRACE_DEBUG=1
 ENV ASPNETCORE_URLS=http://localhost:5000
 ENV DD_PROFILING_LOG_DIR=/var/log/datadog/dotnet
 
-# see https://github.com/dotnet/runtime/issues/77973
-ENV COMPlus_TieredCompilation=0
-
 # Copy the app across
 COPY --from=builder /src/publish /app/.
 
diff --git a/tracer/build/_build/docker/smoke.dotnet-tool.self-instrument.dockerfile b/tracer/build/_build/docker/smoke.dotnet-tool.self-instrument.dockerfile
index 8f9afcdc6c8c..70e10f0b3469 100644
--- a/tracer/build/_build/docker/smoke.dotnet-tool.self-instrument.dockerfile
+++ b/tracer/build/_build/docker/smoke.dotnet-tool.self-instrument.dockerfile
@@ -41,9 +41,6 @@ ENV DD_TRACE_DEBUG=1
 ENV ASPNETCORE_URLS=http://localhost:5000
 ENV DD_PROFILING_LOG_DIR=/var/log/datadog/dotnet
 
-# see https://github.com/dotnet/runtime/issues/77973
-ENV COMPlus_TieredCompilation=0
-
 # Copy the app across
 COPY --from=builder /src/publish /app/.
 
diff --git a/tracer/build/_build/docker/smoke.windows.dockerfile b/tracer/build/_build/docker/smoke.windows.dockerfile
index 7ba449fe8a8d..d4f73c8a83c5 100644
--- a/tracer/build/_build/docker/smoke.windows.dockerfile
+++ b/tracer/build/_build/docker/smoke.windows.dockerfile
@@ -43,9 +43,6 @@ ENV DD_PROFILING_ENABLED=1 \
     DD_PROFILING_LOG_DIR="C:\logs" \
     ASPNETCORE_URLS=http://localhost:5000
 
-# see https://github.com/dotnet/runtime/issues/77973
-ENV COMPlus_TieredCompilation=0
-
 # Copy the app across
 COPY --from=builder /src/publish /app/.
 
diff --git a/tracer/build/_build/docker/smoke.windows.dotnet-tool.dockerfile b/tracer/build/_build/docker/smoke.windows.dotnet-tool.dockerfile
index 7a2674291ce2..3a76ff82444f 100644
--- a/tracer/build/_build/docker/smoke.windows.dotnet-tool.dockerfile
+++ b/tracer/build/_build/docker/smoke.windows.dotnet-tool.dockerfile
@@ -43,9 +43,6 @@ ENV DD_PROFILING_ENABLED=1 \
     DD_PROFILING_LOG_DIR="C:\logs" \
     ASPNETCORE_URLS=http://localhost:5000
 
-# see https://github.com/dotnet/runtime/issues/77973
-ENV COMPlus_TieredCompilation=0
-
 # Copy the app across
 COPY --from=builder /src/publish /app/.
 
diff --git a/tracer/build/_build/docker/smoke.windows.nuget.dockerfile b/tracer/build/_build/docker/smoke.windows.nuget.dockerfile
index 74a3b6d5c107..1beff6f20bef 100644
--- a/tracer/build/_build/docker/smoke.windows.nuget.dockerfile
+++ b/tracer/build/_build/docker/smoke.windows.nuget.dockerfile
@@ -46,9 +46,6 @@ ENV CORECLR_ENABLE_PROFILING=1 \
     DD_PROFILING_ENABLED=1 \
     ASPNETCORE_URLS=http://localhost:5000
 
-# see https://github.com/dotnet/runtime/issues/77973
-ENV COMPlus_TieredCompilation=0
-
 # Copy the app across
 COPY --from=builder /src/publish /app/.
 
diff --git a/tracer/build/_build/docker/smoke.windows.tracer-home.dockerfile b/tracer/build/_build/docker/smoke.windows.tracer-home.dockerfile
index 7f8e02171112..113a0472208b 100644
--- a/tracer/build/_build/docker/smoke.windows.tracer-home.dockerfile
+++ b/tracer/build/_build/docker/smoke.windows.tracer-home.dockerfile
@@ -50,9 +50,6 @@ ENV DD_PROFILING_ENABLED=1 \
     DD_PROFILING_LOG_DIR="C:\logs" \
     ASPNETCORE_URLS=http://localhost:5000
 
-# see https://github.com/dotnet/runtime/issues/77973
-ENV COMPlus_TieredCompilation=0
-
 # Copy the app across
 COPY --from=builder /src/publish /app/.
 
diff --git a/tracer/src/Datadog.Tracer.Native/cor_profiler.cpp b/tracer/src/Datadog.Tracer.Native/cor_profiler.cpp
index 3f54f17c9270..12960d26eab7 100644
--- a/tracer/src/Datadog.Tracer.Native/cor_profiler.cpp
+++ b/tracer/src/Datadog.Tracer.Native/cor_profiler.cpp
@@ -215,6 +215,24 @@ HRESULT STDMETHODCALLTYPE CorProfiler::Initialize(IUnknown* cor_profiler_info_un
         return E_FAIL;
     }
 
+    WSTRING runtimeType = runtime_information_.is_core() ? (runtime_information_.major_version > 4 ? WStr(".NET") : WStr(".NET Core")) : WStr(".NET Framework");
+    Logger::Info("Runtime Information: ", runtimeType, " ", runtime_information_.major_version, ".", runtime_information_.minor_version, ".", runtime_information_.build_version);
+
+    // Check if we have to disable tiered compilation (due to https://github.com/dotnet/runtime/issues/77973)
+    bool disableTieredCompilation = false;
+    bool internal_workaround_77973_enabled = true;
+    shared::TryParseBooleanEnvironmentValue(shared::GetEnvironmentValue(environment::internal_workaround_77973_enabled), internal_workaround_77973_enabled);
+    if (internal_workaround_77973_enabled)
+    {
+        if (runtime_information_.major_version == 5 ||
+            (runtime_information_.major_version == 6 && runtime_information_.minor_version == 0 && runtime_information_.build_version <= 12) ||
+            (runtime_information_.major_version == 7 && runtime_information_.minor_version == 0 && runtime_information_.build_version <= 1))
+        {
+            Logger::Info("Tiered Compilation was disabled due to https://github.com/dotnet/runtime/issues/77973. This action can be disabled by setting the environment variable DD_INTERNAL_WORKAROUND_77973_ENABLED=false");
+            disableTieredCompilation = true;
+        }
+    }
+
     auto pInfo = info10 != nullptr ? info10 : this->info_;
     auto work_offloader = std::make_shared<RejitWorkOffloader>(pInfo);
 
@@ -255,8 +273,14 @@ HRESULT STDMETHODCALLTYPE CorProfiler::Initialize(IUnknown* cor_profiler_info_un
         event_mask |= COR_PRF_DISABLE_ALL_NGEN_IMAGES;
     }
 
-    // set event mask to subscribe to events and disable NGEN images
-    hr = this->info_->SetEventMask2(event_mask, COR_PRF_HIGH_ADD_ASSEMBLY_REFERENCES);
+    DWORD high_event_mask = COR_PRF_HIGH_ADD_ASSEMBLY_REFERENCES;
+    if (disableTieredCompilation)
+    {
+        high_event_mask |= COR_PRF_HIGH_DISABLE_TIERED_COMPILATION;
+    }
+
+    // set event mask to subscribe to events
+    hr = this->info_->SetEventMask2(event_mask, high_event_mask);
     if (FAILED(hr))
     {
         Logger::Warn("DATADOG TRACER DIAGNOSTICS - Failed to attach profiler: unable to set event mask.");
diff --git a/tracer/src/Datadog.Tracer.Native/environment_variables.h b/tracer/src/Datadog.Tracer.Native/environment_variables.h
index 030500859cf7..3f110bcbfa2c 100644
--- a/tracer/src/Datadog.Tracer.Native/environment_variables.h
+++ b/tracer/src/Datadog.Tracer.Native/environment_variables.h
@@ -115,6 +115,9 @@ namespace environment
     // Sets whether the current process must run in CI Visibility mode or not.
     const shared::WSTRING ci_visibility_enabled = WStr("DD_CIVISIBILITY_ENABLED");
 
+    // Enables the workaround for dotnet issue 77973 (https://github.com/dotnet/runtime/issues/77973)
+    const shared::WSTRING internal_workaround_77973_enabled = WStr("DD_INTERNAL_WORKAROUND_77973_ENABLED");
+
 } // namespace environment
 } // namespace trace
 
diff --git a/tracer/test/Datadog.Trace.TestHelpers/EnvironmentHelper.cs b/tracer/test/Datadog.Trace.TestHelpers/EnvironmentHelper.cs
index e66584bec8ef..0e83501bc235 100644
--- a/tracer/test/Datadog.Trace.TestHelpers/EnvironmentHelper.cs
+++ b/tracer/test/Datadog.Trace.TestHelpers/EnvironmentHelper.cs
@@ -189,7 +189,6 @@ public void SetEnvironmentVariables(
         {
             string profilerEnabled = AutomaticInstrumentationEnabled ? "1" : "0";
             environmentVariables["DD_DOTNET_TRACER_HOME"] = MonitoringHome;
-            environmentVariables["COMPlus_TieredCompilation"] = "0";
 
             // Everything should be using the native loader now
             var nativeLoaderPath = GetNativeLoaderPath();