diff --git a/CMakeLists.txt b/CMakeLists.txt
index 6be3449d48..e9d0b3d837 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -174,13 +174,13 @@ endif()
 #
 # Set RPATH for custom install prefixes
 #
-if(APPLE)
+if(APPLE AND NOT DO_NOT_SET_RPATH)
     set(CMAKE_MACOSX_RPATH 1)
 endif()
 
 include(GNUInstallDirs)
 
-if (NOT DEFINED CMAKE_INSTALL_RPATH)
+if (NOT DEFINED CMAKE_INSTALL_RPATH AND NOT DO_NOT_SET_RPATH)
     if(CMAKE_INSTALL_FULL_LIBDIR)
         set(CMAKE_INSTALL_RPATH "${CMAKE_INSTALL_FULL_LIBDIR}")
     else()
diff --git a/CMakeOptions.cmake b/CMakeOptions.cmake
index d995bac5d0..e6e9b11e4e 100644
--- a/CMakeOptions.cmake
+++ b/CMakeOptions.cmake
@@ -120,3 +120,6 @@ option(ENABLE_SYSTEMD
 #  Rust Targets:  https://doc.rust-lang.org/nightly/rustc/platform-support.html
 option(RUST_COMPILER_TARGET
     "Use a custom target triple to build the Rust components. Needed for cross-compiling.")
+
+option(DO_NOT_SET_RPATH
+    "Don't set the RPATH on UNIX systems.")
diff --git a/INSTALL.md b/INSTALL.md
index 14a4886118..9090eea747 100644
--- a/INSTALL.md
+++ b/INSTALL.md
@@ -397,6 +397,12 @@ The following is a complete list of CMake options unique to configuring ClamAV:
 
   _Default: `ON`_
 
+- `DO_NOT_SET_RPATH`: By default RPATH is set in executeables resulting using
+  paths set at build time instead of using system defaults. By setting this
+  `ON` system defaults are used.
+
+  _Default: `OFF`_
+
 - `ENABLE_WERROR`: Compile time warnings will cause build failures (i.e.
   `-Werror`)