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Support analyses of NWB data writing to NWB #4

@jonc125

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@jonc125

Original notes on the kinds of analyses performed by group members:

  • Common aspects
    • Often need to extract subsets of data, e.g. just some of the trials, ROIs, time, etc.
    • General improvements to code reliability & performance possible.
  • Antoine
    • Various options for averaging, smoothing, normalisation
    • Can configure which time region to use for baseline
    • Can show volume & ribbon scans in 2d (projection) or 3d (original coords)
    • GUI will link between different types of plots when clicked
  • Fred
    • Smooths speed data in time using Matlab ‘smooth’ function
    • Finds where speed above threshold => locomotion
    • Baseline: Determines the median grey value for each trace by fitting a kernel function
      • Or from the 20% percentile if flag set in some cases
      • Sometimes subtracts background before calculating
    • Groups ROIs into axons and smooths in time (with some end effects?)
      • Time & df/f for axon is mean of the constituent ROIs
      • Plotting alongside speed data; overlays with detected locomotion periods
      • Trying to detect bursts, and when they start wrt locomotion & puff
      • Using an event detection function from 1997 - experimental? Would be better to use Neuromatic for this kind of thing really.
  • Hana & Sadra
    • Computing dF/F, with baseline taken from mean of initial period
    • Correlations between ROIs, dF/F against speed data - statistics & plots, per trial & averaged over trials
    • Plotting locations of ROIs on raw image
    • Looking at video analysis using third party codes, but still early stages - whisker angles over time, paw location heat map, etc.

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